Department of Biological and Physical Sciences

Professors: Elizabeth A. Colby Davie (Chairperson), Stuart I. Cromarty, David J. Crowley, Edward J. Dix, Georgi Y. Georgiev, Michele L. Lemons, Jessica A. McCready, Brian K. Niece, Steven J. Theroux; Associate Professors: Soraya Betancourt-Calle, Teresa Herd, 3:2 Engineering Director, Benjamin J. Knurr; Assistant Professors: Nikos Lessios, Laura Marcotte, Erin Tuttle; Assistant Professors of Practice: Anthony Sacino, Jessica Whitt, Director of the Center for Neuroscience; Visiting Assistant Professors: Stephanie J. Bouley, Douglas K. Reilly; Lecturer: Sandra Nedelescu.

Mission Statement 

The Department of Biological and Physical Sciences is dedicated to preparing students to live and work in a changing world by ensuring competency in the natural sciences and scientific inquiry. The department strives to provide a basic understanding of classical and contemporary scientific concepts in these areas. While developing an understanding of the scientific process and its application, the following critical skills are stressed: observation, inquiry, data collection, analysis, communication, and correlation of scientific concepts. The department prepares students for careers and professional opportunities in the sciences as well as for life-long learning in the context of a liberal arts curriculum in the Catholic tradition.

Programs of Study and Career Options 

The Department of Biological and Physical Sciences offers majors in the following disciplines:

  • Biology
  • Biology with a Concentration in Neuroscience and Behavior
  • Biotechnology and Molecular Biology
  • Chemistry
  • Environmental Science
  • Neuroscience
  • Pre-Clinical Health Science

The Department also offers minors in Biology, Environmental Science, Chemistry, and Physics, and it co-sponsors concentrations in Pre-Physical Therapy and Pre-Occupational Therapy with the Department of Health and Human Services. Research opportunities are available at the University and at nearby institutions (e.g., University of Massachusetts Medical School and the Biotechnology Park). Students interested in teaching science in the public schools should work with a science faculty member and a member of the Education Department in planning their course of study. The Department also offers courses for non-majors.

Students who wish to pursue careers in medicine, dentistry or one of the many other health professions must complete the necessary prerequisites for admission to the health profession schools of their choice. These individuals should consult their academic advisors and the Health Professions Advisor, Dr. Steven Theroux, when designing their course of study. The Health Professions Program helps students meet the admissions requirements for these professional programs. The Department has agreements with several institutions that offer degrees in the health professions. Students interested in Allopathic or Osteopathic Medicine, Podiatric Medicine, Pharmacy, Physical Therapy, Optometry, Physician Assistant Studies, Nursing, or Biotechnology should discuss these agreements with the Health Professions Advisor, Prof. Steven Theroux.

The University has established collaborative programs of study in Engineering with the University of Notre Dame and with Washington University in St. Louis. Students spend three years at Assumption University completing foundational courses in math and science before transferring to Notre Dame or Washington University to complete engineering studies. Interested students should contact Professor Teresa Herd, Director of the Engineering Program.

The University also has agreements with several graduate schools. In conjunction with Duke University, we offer combined B.A. and Master’s degree programs in Environmental Science Management and Forestry Management. There are several options for students interested in the legal profession, especially those interested in practicing environmental law or intellectual property law. Science students interested in learning more about these programs should see Professor Erin Tuttle.

The Department offers a post-graduate program for those who have a bachelor’s degree in an area other than Biology and who are interested in pursuing admission to a health professions program (e.g., medicine, dentistry, pharmacy, etc.) Details about this certificate program can be obtained from the Health Professions Advisor, Dr. Steven Theroux.

Students who graduate with an undergraduate degree in science can pursue employment in industry, government, or in an educational setting. Some of our students pursue graduate studies in science, one of the health professions, business or law. Upon the completion of the appropriate graduate program our students can pursue research careers in environmental management, or in the biotechnology, pharmaceutical and chemical industries. They can also develop careers in elementary, secondary and higher education, or in the health professions, business management, government, or legal profession.

Student Research – Summer Opportunities 

Department faculty members oversee research programs on campus that engage upper-level students in the projects associated with their research interests. Summer research positions that provide a stipend are available on a competitive basis. Assumption students have been accepted into prestigious summer research programs at major research institutions around the country. The sponsoring institutions for this research include the National Science Foundation, the National Institutes of Health, and the American Cancer Society.

Articulation Agreements in the Science and Health Professions 

Assumption University holds a wide range of agreements with graduate institutions in the health sciences. For a complete list, see the “Articulation Agreements” section above and/or contact the Health Professions Advisor, Prof. Steven Theroux, stheroux@assumption.edu 

Engineering Programs with the University of Notre Dame (3:2) and Washington University, St. Louis (3:3) 

Students interested in pursuing one of the engineering programs should take the technical courses listed below in their first year at Assumption. Careful planning is important to meet the prerequisites for admission to Notre Dame or Washington University. Interested students should meet with the dual degree engineering program director, Prof. Teresa Herd, to start planning their curriculum.

First Year Courses for 3:2 or 3:3 Engineering, Various Fields 

Assumption MajorNotre Dame/Washington University Engineering MajorRecommended First-Year Technical Courses 
FallSpring
BiologyBiomedical Engineering

MAT 117 OR MAT 131H Calculus I 

CHE 131 Chemistry I 

BIO 160 Concepts in Biology

MAT 118 OR MAT 132H Calculus II 

CHE 132 Chemistry II 

BIO 210 Genetics 

PHY 213 Introduction to Engineering

ChemistryChemical Engineering

MAT 117 OR MAT 131H Calculus I 

CHE 131 Chemistry I 

BIO 160 Concepts in Biology

MAT 118 OR MAT 132H Calculus II 

CHE 132 Chemistry II 

PHY 213 Introduction to Engineering

Environmental ScienceEnvironmental Engineering 

MAT 117 OR MAT131H Calculus I 

CHE 131 Chemistry I 

ENV 150 Introduction to Environmental Science

MAT 118 OR MAT132H Calculus II 

CHE 132 Chemistry II 

PHY 213 Introduction to Engineering 

BIO 160 Concepts in Biology

MathAerospace Engineering 

MAT 117 OR MAT 131H Calculus I 

PHY 201H Honors Physics I 

CSC 120 Statistics Programming in Python

MAT 118 OR MAT 132H Calculus II 

PHY 202H Honors Physics II

PHY 213 Introduction to Engineering 

Civil Engineering 
Electrical Engineering 
Mechanical Engineering
Systems Engineering

MAT 117 OR MAT131H Calculus I 

PHY 201H Honors Physics I 

CSC 117 Introduction to Programming in C++

MAT 118 OR MAT132H Calculus II 

PHY 202H Honors Physics II 

PHY 213 Introduction to Engineering 

CSC 250 Intermediate Programming

Computer Science Computer Engineering 

MAT 117 OR MAT131H Calculus I 

PHY 201H Honors Physics I 

CSC 117 Introduction to Programming in C++

MAT 118 OR MAT132H Calculus II 

PHY 202H Honors Physics II 

PHY 213 Introduction to Engineering 

CSC 250 Intermediate Programming

Preparation for Teaching Science at the Secondary Level 

Students interested in seeking certification to teach high school biology or chemistry should consider a Major in Biology or Chemistry and a Major in Education, Secondary License. Application to the Education Major must be made by April 30 of the sophomore year. Please see a complete description of procedures and policies in the Department of Education section of the catalog. A student should carefully plan a course of study in conjunction with advisors in both departments (Education and Biological and Physical Sciences).

Biology – Field of Knowledge Competencies:

Chemistry – Field of Knowledge Competencies:

Pre-Medical/Pre-Dental 

As a liberal arts university, Assumption offers students the knowledge necessary for entrance to and success in medical and/or dental school. Most students interested in pursuing a career in Medicine or Dentistry major in Biology or Pre-Clinical Health Science. However, it is possible to choose other majors and still prepare for such a career. Although there is no universal standard for medical school admissions, most school requirements would be fulfilled by inclusion of the following courses:

  • BIO 160 Concepts in Biology
  • One from the following three Biology courses:
  • CHE 131–132 General Chemistry I and II (Note: MAT114 is a pre-requisite for CHE 132)
  • CHE 201–202 Organic Chemistry I and II
  • PHY 201–202 General Physics I and II
  • ENG 130 Writing in the University
  • ENG 140 Literature and Its Interpretations

Additional courses that are usually highly recommended include:

  • CHE 414 Biochemistry
  • MAT 117 Calculus I or MAT 131 Honors Calculus I
  • ECO 115 Statistics with Excel or PSY 224 Statistics
  • Courses in Psychology and Computer Science
  • Additional courses in Biology, Chemistry, and Mathematics are helpful.

Note these courses reflect a suggested course load. Students should contact their desired schools and Dr. Steven Theroux before committing to a plan of study.

Medical Technology Option (Biology Major) 

The Medical Technology Option is designed to offer students the background necessary to apply for admission to a hospital-affiliated school of Medical Technology. This option can be completed in three or four years at Assumption before entering a school of Medical Technology. The three-year program is described here. During the first three years while the student is at Assumption University, he/she should complete:

  • Four courses in Chemistry, including Organic Chemistry
  • Two courses in Physics
  • Seven courses in Biology , including Microbiology and Immunology
  • One course in Mathematics at the level of MAT 114 or above

In addition, other curriculum requirements to fulfill the Bachelor of Arts program at Assumption must be taken during the first three years of the program when planned in conjunction with a faculty advisor in the Department of Biological and Physical Sciences. It is important for a student interested in this option to indicate his/her interest in the first year and to plan the program carefully. Three years of study (30 courses) as a Biology major at Assumption are followed by one year of training and study in an approved hospital school of Medical Technology. Upon completion of the hospital year, the student will receive a Bachelor’s degree from Assumption and will be eligible to take the National Registry Exam in Medical Technology. Participation in Assumption’s undergraduate Medical Technology Option does not guarantee admission to a School of Medical Technology.

Health Professions Preparation 

Students who wish to pursue careers in medicine, dentistry or one of the many other health professions must complete the necessary prerequisites for admission to the health profession schools of their choice. These individuals should consult their academic advisors and the Health Professions Advisor, Dr. Steven Theroux, when designing their course of study. The Department has agreements with several institutions that offer degrees in the health professions. Students interested in Allopathic or Osteopathic Medicine, Podiatric Medicine, Pharmacy, Physical Therapy, Optometry, Physician Assistant Studies, Nursing, or Biotechnology should discuss these agreements with the Health Professions Advisor, Prof. Steven Theroux. Students who plan to pursue a graduate degree in a health profession should be aware of the timetable in which to fulfill their requirements, which include admissions exams and letters of reference from the Health Sciences Committee. Students should be prepared for entrance exams in their junior year and request a letter of reference at that time. Students must contact Dr. Theroux at least two weeks before the scheduled Committee meeting times in the second week of October, the second week of February, and the second week of May. The letters will usually be ready within four to five weeks of the meeting.

Programs of Study

Courses

BIO 102: HUMAN BIOLOGY IN HEALTH AND DISEASE

Credits 4

A course for non-science majors that focuses on selected functional systems of the body, the organs that compose them, and the interactions among them. Special attention will be given to disease processes. In these systems laboratory work (one three-hour session per week) will include studies of physiological concepts at the cellular and systems levels. This course is especially designed for students majoring in Social and Rehabilitation Services or Psychology, or students seeking background for courses in Anthropology and other social sciences.

BIO 105: HUMAN HEREDITY

Credits 3
This course presents an introduction to the principles of human genetics. Major topics covered include cell division and the distribution of genetic material, embryonic development and the role of teratogens; Mendel’s experiments, inheritance patterns in human families; the interaction of genes and the environment; the structure and function of DNA; personal genomics; and genetic technologies. An historical approach is used and most genetic principles are introduced by examples from human medical genetics. Two or three integrated lecture-laboratory sessions per week.

BIO 110: NUTRITION

Credits 3
This course will explore the basic principles of human nutrition. Topics to be covered include nutrient classes, nutritional guidelines, nutrition-related diseases and disparities in access to healthy foods. This course will also cover controversial topics in nutrition such as GMOs and fad dieting. This will be an interactive course that will require students to use the scientific method and will include in-class research, data collection, presentations and discussions. Two or three integrated lecture-laboratory sessions per week.

BIO 115: MATTERS AND MYSTERIES OF YOUR BRAIN

Credits 3
The brain is the most complex and least understood organ in our bodies. It is fascinating to consider that the brain is required for a vast array of functions including learning and memory, motor movement, and perception of our environment. The brain’s vital role in our daily life is indisputable, yet we do not fully understand the fundamental underpinnings of brain function. For this reason, the brain is referred to as the last frontier of science. In this course, student-driven approaches will be used to explore what is known and what is not yet fully understood about brain function through the use of case studies of humans suffering from brain injury, hypothesis-driven experimentation, and critical examination of recent science findings as described by the media. Students will refine their practice of the scientific method while enhancing critical thinking skills. Two or three integrated lecture-laboratory sessions per week.

BIO 125: BACKYARD BIOLOGY

Credits 3
Biology is the science of life – and life happens all around us. In this course, we will explore fundamental concepts of biology using real-life examples encountered for example in your kitchen or backyard. We will focus on the principles of ecology and evolution, while tackling contemporary problems of global importance – climate change and biodiversity decline. The integrated laboratory experience consists of self-guided explorations of plants, animals, and other organisms commonly found in the Northeastern USA, as well as simple at-home experiments and simulations. This course aims to broaden your horizons and instill an appreciation for the creatures large and small with whom we share the world. By exploring the life that happens right outside your door, you will not only learn basic biological facts, but more importantly the ecological connections that make life on Earth possible and enjoyable! Two or three integrated lecture-laboratory sessions per week.

BIO 140: INQUIRY BIOLOGY FOR EDUCATORS

Credits 4
In this course, students learn fundamental concepts and models associated with three major sub-disciplines of biology – genetics, ecology, and evolution. The course heavily emphasizes the use of open-ended, problem-solving methods of teaching and learning to help students develop their own functional understanding of the major concepts. A significant part of students’ problem-solving work involves the use of computer technology, including the use of concept mapping and computer simulations to facilitate concept development. The course is intended for students planning on pursuing a career in elementary or middle school education. As such, particular attention is given to understanding common misconceptions that children have concerning learning about biological phenomena and considering the ramifications of these misconceptions for the development of effective classroom instruction. At least twice during the term, students will be expected to teach “mini” lessons in the biological sciences. The course includes a lab component and meets six hours a week.

BIO 150: BIOLOGICAL PRINCIPLES

Credits 4
An introductory course that provides a strong foundation in aspects of biological science that are particularly relevant to nursing students. The course focuses on the chemical basis of life, cell structure and function, genetic information, and energetics and regulation of living systems. Together with the laboratory, this class introduces students to techniques and approaches used in science. Three lecture periods and one laboratory meeting per week. Should be taken by nursing students in their first year.

BIO 160: CONCEPTS IN BIOLOGY

Credits 4
An introductory course required of all science majors that emphasizes major concepts in biological science: structure and function, homeostasis, energetics, perpetuation, and evolution of living organisms. The laboratory will introduce students to the techniques and approaches used in biology. Three lectures and one laboratory period each week. Should be taken by intended science majors in the first year.

BIO 207: DARWIN’S DESCENT OF MAN

Credits 3
People have long struggled with the notion that humans have descended from non-human ancestors. In his 1871 volume Descent of Man, Charles Darwin comprehensively applies his views on evolutionary theory and shared ancestry, including his adaptive mechanisms of natural and sexual selection, to human beings. Using countless examples, rational arguments, and the voice and writing style of a Victorian gentleman, Darwin convincingly demonstrates that humans gradually evolved from animals. The book, therefore, challenges its readers with what it means to be human as Darwin addresses the emergence of language, culture, morality, notions of beauty, sexual attraction, and the origin of race from our animal ancestors. This course helps students learn to read Darwin’s rich text, to understand the extraordinary depth, collaborative style, and limitations of his science, to engage critically with the enduring questions and tensions the text raises, and to reflect on the ways that Darwin’s work still resonates in biology and culture today.

BIO 210: GENETICS

Credits 4
A brief survey of Mendelian and cytological genetics with most emphasis placed on recent advances in molecular genetics. Replication, translation, and transcription of the genetic material receive detailed study. Three lectures and one laboratory per week.

BIO 220: INVERTEBRATE ZOOLOGY

Credits 4
A survey of invertebrate animals from protozoans through invertebrate chordates, emphasizing their functional organization, modes of reproduction, ecological roles, and evolutionary relationships. In the laboratory, we will examine representative living and preserved specimens, concentrating on their structure and behavior. Three lectures and one laboratory or field trip each week.

BIO 225: BIOLOGY OF FISHES

Credits 3
This course is taught at the New England Aquarium by faculty of the Marine Studies Consortium, though it has an Assumption instructor of record who acts as a liaison. Biology of Fishes covers aspects of the evolution, biology, ecology, taxonomy, physiology, and structure of fish. The diversity of extinct and extant fishes will be emphasized. Physiological, behavioral and morphological adaptations for life in the diverse habitats within water will be examined. The role of evolution as the driving force behind the great diversity of fishes will be a constant theme.

BIO 230: PLANT BIOLOGY

Credits 4
This course provides an introduction to the biology of plants. Among the topics considered are the role of plants in the biosphere, plant form and function, and the evolution of plants. In the laboratory, students examine representatives of the major groups of plants and learn the fundamentals of plant tissue culture techniques in order to study plant growth and development. Field work includes trips to a variety of local habitats. Three lectures and one laboratory or field trip each week.

BIO 240: HUMAN ANATOMY

Credits 4
Anatomy is the study of the structure of organisms. In this course we will study human anatomy in four regions: (i) back, (ii) upper and lower limbs, (iii) thorax, abdomen and pelvis, and (iv) head and neck. We will focus on anatomy of the human body and emphasize how structure affects function. Major topics covered in each region include muscles, bones, blood vessels and nerves. This course will consist of three one-hour lectures and one three-hour laboratory each week.

BIO 250: MICROBIOLOGY

Credits 4
Microorganisms, especially bacteria and viruses, are studied with respect to their morphological characteristics, growth and metabolism, genetics and environmental significance. The role of microorganisms as pathogens and the control of microorganisms are also considered. Laboratory techniques include sterilization, isolation, and culturing. Three lectures and one laboratory per week.

BIO 260: BIOINFORMATICS

Credits 4
Bioinformatics is the umbrella term for a wide range of methods and tools used to analyze large and complex biological data sets, especially DNA and RNA sequence data. This course introduces students to broadly applicable bioinformatic methods. Students will learn to access and use information from public databases, align homologous sequences, construct and interpret phylogenetic trees, and extract information from genomes using a variety of computational tools, including the use of basic command line interface. Relevant primary literature will be analyzed and discussed. The laboratory portion of the course is dedicated to practice with the analysis tools introduced in lectures, and to student projects. Students will work in groups to explore real data sets, select and apply suitable bioinformatic methods, interpret analysis results in the context of published works, and present their findings to the class. This course counts as an elective towards the Biology, Biotechnology, and Data Analytics majors. Three lectures and one laboratory per week.

BIO 270: BIOLOGY OF WHALES

Credits 3
This course is taught remotely by faculty of the Marine Studies Consortium, though it has an Assumption instructor of record who acts as a liaison. Biology of Whales explores the biology, ecology, conservation, and management of whales, dolphins, and porpoises.

BIO 275: SPECIAL TOPICS IN BIOLOGY

Credits 3
This special topics course will explore an area of biology using the literature, and if appropriate, a cross-disciplinary approach. The course will allow the students and faculty an opportunity to investigate areas of biology that are not part of the regular curriculum.

BIO 280: SENSORY SYSTEMS

Credits 4
Sensory Systems provides an understanding of how organisms see, hear, smell, taste, and feel sensations. In this course, we discuss the physiological and cellular mechanisms that allow organisms to receive sensory information. We introduce reflex pathways in organisms with complex nervous systems, and then compare these to how organisms with reduced nervous systems carry out stereotyped behavior. These simpler examples of sensory processing and behavior provide a foundation to understand how information is processed by the early stages of central nervous systems for more complex behavior. Our focus is on the mechanisms and sensory pathways the nervous system uses to process sensory information and control movement. Using comparative animal model systems, topics include sensory transduction and the sensory physiology for the best known sensory systems (olfactory, visual, somatosensory, auditory, gustatory) and models of sensory processing. We also ask: what can we learn from animals with senses that primates are currently not known to have, such as magnetic and electric senses? These are currently active areas of animal research.

BIO 291: INTERNSHIP IN BIOLOGY

Credits 3
Directed study within an internship program. The student will be expected to keep a journal detailing the internship. The student will also be expected to write a paper, usually approximately 10 pages in length, summarizing an area related to the internship experience. An evaluation by the on-site supervisor will be considered when determining the grade. The student will be required to have a cumulative G.P.A. of 3.0 to enroll.

BIO 310: ANIMAL BEHAVIOR

Credits 4
This course will initially approach the study of animal behavior from the physiological perspective: the neural basis of behavior (the nervous circuits responsible for sensory input and integration and motor output) will be studied in some detail. Subsequently, the emphasis will shift to the contribution of ecological, developmental, and evolutionary forces to shaping the ultimate behavior output. Three lectures and one three-hour laboratory each week.

BIO 320: ORGANIC EVOLUTION

Credits 3
This course is an introduction to genetic changes in populations over time and to the models and evidence we use to identify and explain those changes. Topics include: influence of the environment, genotype-phenotype connections, Hardy-Weinberg equilibrium, genetic variation, genetic drift, in-breeding, natural selection, gene flow, speciation, phylogeny, macro-evolutionary trends, and the fossil record.

BIO 340: MOLECULAR AND CELLULAR BIOLOGY

Credits 4
This course focuses on the structure and function of the eukaryotic cell. The role of cellular membranes in basic physiological processes is discussed in detail. The physiological roles of the extracellular matrix, the cytoskeleton, and various subcellular structures are also addressed. Finally, the student will be introduced to the processes that govern cellular division and cellular evolution. When possible, the course topics are related to the development of various human maladies, such as cancer and AIDS. The laboratory exposes the students to several classical techniques used in cell biology and to a number of modern methods used by protein chemists and molecular biologists.

BIO 350: MARINE MAMMALS: BIOLOGY AND CONSERVATION

Credits 3
This course is designed to familiarize students with the biology and natural history of marine mammals. Emphasis is placed on whales, dolphins, and seals of the western North Atlantic, but species from all over the world will be discussed. Topics to be considered include evolution, anatomy, behavior, field identification, the history of whaling, and contemporary conservation problems. Hands-on activities include one evening laboratory work (harbor porpoise or seal dissection) and marine mammal survey on Massachusetts Bay.

BIO 360: ECOLOGY

Credits 4
In this course, students interpret published data, critique some original papers, and participate in class discussion on the following topics: limits on species distributions, demography, population growth and regulation, interactions of species, energy flow, nutrient cycling, community dynamics, succession, and patterns of species diversity. In laboratory, students participate in class exercises, and design, perform, and report their own group field projects. Three lectures and one three-hour laboratory per week.

BIO 370: GENERAL PHYSIOLOGY

Credits 4
Human and animal physiology, with a comparative approach to the study of muscle contraction; blood circulation and respiration; metabolic and temperature controls; digestion and excretion; and nervous, sensory, and endocrine functions. The laboratory exercises focus on the investigation of basic concepts of animal and human physiology at the cellular and systems levels. Three lectures and one three-hour laboratory period each week.

BIO 375: MILESTONES IN NEUROSCIENCE

Credits 3
Using a critical examination of the primary literature as a tool, this course explores landmark advances within the field of neuroscience. Students gain a deeper understanding of neurobiological themes such as neurophysiology, neuroplasticity, neural development and communication between select model animal systems. Classic articles that are foundational to the field of neuroscience are thoroughly dissected to gain an historical appreciation of advances in the field. These are contrasted with recent articles to appreciate the advances in neuroscience research techniques. By contrasting major historical advances with more recent work, students weigh the implications of these findings at the time of publication and learn to critically assess the significance of recent findings. Students gain a deeper understanding of highlighted milestone advances in neurobiology.

BIO 380: THE BIOLOGY OF CANCER

Credits 3
This course will explore the biology of cancer. Beginning with an examination of the personal, social and economic consequences of this disease, it will move to a focus on the cellular and molecular biology of cancer. Specially, it will study the nature of cancer, the role of viruses in cancer, cellular oncogenes, cellular signaling mechanisms, tumor suppressor genes, and the maintenance of genomic integrity. Other topics to be examined include: the cell cycle, apoptosis, cellular immortalization, tumorigenesis, angiogenesis and metastasis. Finally, this course will examine how modern molecular medicine is being used to treat cancer.

BIO 390: EXERCISE PHYSIOLOGY

Credits 4
This advanced course is designed to provide students with applied knowledge relative to the human’s physiologic responses to acute and chronic exercise stress. Students’ basic knowledge of neuromuscular physiology, energy metabolism, cardiovascular and respiratory physiology will be honed to focus on human exercise response, with the focus of the course being on applications to exercise training and programming, sport, nutrition, youth, aging, and disease. Laboratory exercises will enable practical skills to be gained in measuring and testing for physiological markers of human readiness and response to exercise.

BIO 415: PRINCIPLES OF NEUROSCIENCE

Credits 4
This course introduces students to the rapidly growing field of neuroscience, which is the study of the nervous system. Our nervous system shapes our every thought, emotion and sensation. Students will gain an understanding of the underlying neural basis of how we perceive the world. This course begins with an anatomical approach and then integrates physiological, cellular, molecular and functional approaches. Topics range from how cells in the brain communicate with one another, to current diagnostic and research technology, to the biological basis of movement, and includes the study of disease and injury to the brain, such as Alzheimer’s disease, Parkinson’s disease and stroke. Three lectures and one three-hour laboratory each week.

BIO 430: COMPARATIVE PHYSIOLOGY

Credits 4
This course combines a brief review of fundamental principles of animal physiology with an in-depth discussion of how these principles are modified and shaped by environmental and ecological pressures. The functional significance of physiological adaptation to an animal’s environment is emphasized by describing various mechanisms of regulation of physiological variables (temperature, metabolism, oxygen consumption, water retention, circadian rhythms) in extremely different environmental conditions. Three lectures and one three-hour laboratory each week.

BIO 440: BIOTECHNOLOGY IN THEORY AND PRACTICE

Credits 4
This course integrates the disciplines of cellular biology, molecular biology, and protein chemistry through a series of related experiments. The course will expose students to: 1) recent journal articles within the scientific literature; 2) selected methods, techniques, and instruments used in biotechnology; and 3) strategies that can be employed to solve interesting biological problems. The laboratory experience will introduce the student to DNA amplification by the polymerase chain reaction; oligonucleotide-directed site specific mutagenesis; gel electrophoresis; isolation of protein, DNA and RNA; gene cloning; DNA sequencing; cell culture; gene expression in mammalian cell lines; and Southern hybridization analysis. Class meets six hours per week for lecture, laboratory, and discussion.

BIO 480: SEMINAR IN LIFE SCIENCES

Credits 3
An overview of a defined scientific topic (such as the process of cell division) will be presented, and then recently published articles on this topic will be discussed in detail. As part of the course requirements, each student will be asked to present one or more assigned journal articles to the class. The course is designed to increase the student’s knowledge of an active area of scientific inquiry and to enhance the student’s reading, data analysis, and oral presentation skills.

BIO 540: FOUNDATIONS IN BIOTECHNOLOGY

Credits 3
Provides an interdisciplinary, state-of-the-art introduction to biotechnology. Covers the molecular foundations of biotechnology, molecular microbiology, receptor pharmacology, drug development processes, biotech process development and scale-up, drug approval and regulatory affairs, genomics, microarray analysis, proteomics, computational biology, molecular modeling, analytical biotechnology, and bioterrorism and biotechnology. This course is offered at Northeastern University as BIOT 5120.

BIO 541: CELL CULTURE PROCESSES FOR BIOPHARMACEUTICAL PRODUCTION

Credits 3
Covers the principles and concepts involved in the development of mammalian and other types of cell culture processes for the manufacturing of biopharmaceutical products such as monoclonal antibodies and recombinant proteins. Topics include protein expression and clone generation, batch and perfusion processes and media development, bioreactor operations and scale-up, and innovations in cell culture processes. Regulatory concepts include quality assurance in a cGMP environment. This course is offered at Northeastern University as BIOT 5631.

BIO 542: THE BIOTECHNOLOGY ENTERPRISE

Credits 2
Exposes students to the business of biotech from scientific discovery startup through its product launch and subsequent organizational and scientific pipeline growth. Topics include scientific discovery, biotech-related funding and organizational structures, regulatory and clinical trial considerations, biotech alliances, patient access, ethics and compliance, and commercialization and growth while meeting unmet patient or consumer needs in this highly regulated industry. Although the focus is on the highest regulated standards in biopharma, the course also touches upon various aspects of other biotechnology domains. This course is offered at Northeastern University as BIOT 5219.

BIO 543: BASIC BIOTECHNOLOGY LAB SKILLS

Credits 1
Introduces selected key skills and techniques central to life sciences research. Combines hands-on training in basic laboratory skills with lecture and live demonstration. Laboratory exercises highlight the importance of precision/accuracy in dispensation of liquids and in the preparation of solutions and standards, documentation and record keeping, and maintaining a safe and sterile work environment while performing scientific research. This course is offered at Northeastern University as BIOT 5145.

BIO 544: PROTEIN CHEMISTRY

Credits 3
Describes proteins (what they are, where they come from, and how they work) in the context of analytical analysis and molecular medicine. Discusses the chemical properties of proteins, protein synthesis, and the genetic origins of globular proteins in solution, membrane proteins, and fibrous proteins. Covers the physical intra- and intermolecular interactions that proteins undergo along with descriptions of protein conformation and methods of structural determination. Explores protein folding as well as protein degradation and enzymatic activity. Highlights protein purification and biophysical characterization in relation to protein analysis, drug design, and optimization. This course is offered at Northeastern University as CHEM 5620.

BIO 545: MOLECULAR CELL BIOLOGY FOR BIOTECHNOLOGY

Credits 3
Integrates biochemistry and molecular biology in the cellular context. Includes the organization and replication of genomes, principles and methods for genetic manipulation, the regulation of gene expression, and the structure and function of organelles. Emphasizes protein synthesis, including translation, post-translational modifications, and translocations of proteins within the cells and secretion. This course is offered at Northeastern University as BIOL 6299.

BIO 546: EXPERIMENTAL DESIGN AND BIOSTATISTICS

Credits 2
Explores the principles of experimental design and statistical analysis. Emphasizes research in the molecular and biological sciences and biotechnology. Topics include probability theory, sampling hypothesis formulation and testing, and parametric and nonparametric statistical methods. This course is offered at Northeastern University as BIOT 6214.

BIO 547: BIOINFORMATICS PROGRAMMING

Credits 4
Focuses on the fundamental programming skills required in the bioinformatics industry. Focuses on Python and R as the main programming language used. Topics include string operations, file manipulation, regular expressions, object-oriented programming, data structures, testing, program design, and implementation. Includes substantial out-of-classroom assignments. This course is offered at Northeastern University as BINF 6200.

BIO 548: BIOINFORMATICS COMPUTATIONAL METHODS 1

Credits 4
Offers the first semester of a two-semester sequence on the use of computers in bioinformatics research. Offers students an opportunity to work with current methods and computational algorithms used in contemporary sequence analysis. Teaches practical skills necessary to manage and mine the vast biological information being generated and housed in public databases. Emphasizes the use of Python as the primary computer language and requires students to learn and understand basic computer logic and syntax, including an introduction to scalars, arrays, hashes, decision statements, loops, subroutines, references, and regular expressions. A focus on fundamental skills, including the command line interface found in the Linux operating system, is designed to prepare students for second-semester applications. This course is offered at Northeastern University as BINF 6308.

BIO 549: BIOINFORMATICS COMPUTATIONAL METHODS 2

Credits 4
Designed to build upon the core topics covered in BINF 6308, i.e., use of the computer as a tool for bioinformatics research. Builds upon the Python language fundamentals covered during the first semester but requires students to apply these fundamentals to a semester-long project. The project includes protein family analysis, multiple sequence analysis, phylogeny, and protein structure analysis. Additionally, students have an opportunity to learn to build, load, connect, and query custom MySQL databases, and parse command line flags. This course is offered at Northeastern University as BINF 6309.

BIO 550: STATISTICS FOR BIOINFORMATICS

Credits 4
Introduces the concepts of probability and statistics used in bioinformatics applications, particularly the analysis of microarray data. Uses statistical computation using the open-source R program. Topics include maximum likelihood; Monte Carlo simulations; false discovery rate adjustment; nonparametric methods, including bootstrap and permutation tests; correlation, regression, ANOVA, and generalized linear models; preprocessing of microarray data and gene filtering; visualization of multivariate data; and machine-learning techniques, such as clustering, principal components analysis, support vector machine, neural networks, and regression tree. This course is offered at Northeastern University as MATH 7340.

CHE 102: CHEMISTRY FUNDAMENTALS FOR HEALTH SCIENCE

Credits 1
This course aims to prepare students who have not completed general and organic chemistry for upper-level biology courses, especially BIO 370 General Physiology. Topics covered include atoms and molecules, properties and concentration of solutions, acids and bases, thermodynamics, kinetics, and basic organic chemistry with an emphasis on biological and healthcare-related examples.

CHE 105: EVERYDAY CHEMISTRY

Credits 3
This course is designed for non-majors to better understand the chemistry that they interact with in their everyday lives. Even though chemistry has a constant and ubiquitous impact on our lives, most people are unaware of the science behind the products that they use every day. Emphasis will be on the connection between fundamental chemical properties and concepts and the student’s everyday lives. Topics will be organized around the chemistry seen in different household areas such as the kitchen, bathroom, laundry room, and garage. Two or three integrated lecture-laboratory sessions per week.

CHE 131–132: GENERAL CHEMISTRY I AND II

Credits 4

Fundamental principles of chemistry. Topics covered in CHE 131 include: matter and measurement, atomic and electronic structure, stoichiometry, gases, bonding, and solutions. In CHE 132: chemical equilibria (gases, solubility), acids and bases, electrochemistry, thermochemistry, nuclear and coordination chemistry. Emphasis is placed on problem solving. Laboratory work includes Qualitative Analysis. CHE 131 is a prerequisite for CHE 132. Intended science majors should take this series in their first year.

CHE 201–202: ORGANIC CHEMISTRY I AND II

Credits 4
The chemistry of organic compounds (the compounds of carbon) is studied. The topics include covalent bonding, molecular structure, and resonance; constitutional, geometric, and optical isomerism; the reactions of organic compounds through their functional groups; the nucleophilic, electrophilic, and free radical reaction mechanisms; and spectroscopy. These theoretical and practical principles are applied to the solution of such organic chemical problems as structure determination, chemical synthesis of desired molecules, the effect of structure on properties, and the biological roles of organic molecules. This full-year course meets the needs of students who expect to pursue graduate studies in natural sciences and also of those who plan to enter professional schools.

CHE 275: SPECIAL TOPICS IN CHEMISTRY

Credits 3
This special topics course will explore an area of chemistry using the literature, and if appropriate, a cross-disciplinary approach. The course will allow the students and faculty an opportunity to investigate areas of chemistry that are not part of the regular curriculum.

CHE 291: INTERNSHIP IN CHEMISTRY

Directed study within an internship program. The student will be expected to keep a journal detailing the internship. The student will also be expected to write a paper (usually approximately 10 pages in length) summarizing an area related to the internship experience. An evaluation by the on-site supervisor will be considered when determining the grade. The student will be required to have a cumulative G.P.A. of 3.0 to enroll.

CHE 311–312: PHYSICAL CHEMISTRY I AND II

Credits 4
An intensive study of the structure and interconversions of matter in its several states. Intra- and inter-molecular forces, thermodynamics, equilibria, electrochemistry, kinetics, and statistical and quantum mechanics are considered.

CHE 315: ANALYTICAL CHEMISTRY

Credits 4
A study of the major methods of chemical analysis, including statistics in evaluating the error associated with measurements, the systematic treatment of acid-base equilibria, introductory electrochemistry and spectrophotometry, and the theory of separations (chromatography). Three lectures and one three-hour laboratory per week.

CHE 316: INORGANIC CHEMISTRY

Credits 4
A study of the structure and properties of the elements and their compounds. Topics covered are atomic structure, periodic relationships, molecular bonding, acid-base systems, and coordination compounds. Laboratory work focuses on the interaction between experiment and theory in understanding and predicting chemical phenomena. Three lectures and one laboratory period per week.

CHE 318: ENVIRONMENTAL CHEMISTRY

Credits 4
A specialized knowledge of chemistry is needed in order to identify, understand, and solve environmental problems. This course will be an in depth study of the chemistry of environmental issues and pollutants. Students will learn the mechanisms of important chemical reactions, as well as relevant analytical techniques related to environmental chemistry. In the lab, students will combine field work, analytical chemistry, and remediation techniques during their investigation of environmental problems.

CHE 414: BIOCHEMISTRY

Credits 4
The major classes of biochemicals, carbohydrates, proteins, lipids, and nucleic acids are studied with particular attention to the relationship between their chemical structures and biological functions. Specific topics include (but are not limited to) biocatalysis, receptors, membrane structure, metabolism, biosynthesis, and energy production.

CHE 416: MOLECULAR STRUCTURE AND CHARACTERIZATION

Credits 4
A detailed study of current chemical bonding theories and characterization techniques. Topics covered include molecular symmetry, molecular orbital theory, and computer molecular modeling. Molecular characterization with electronic, vibrational, and nuclear magnetic resonance spectroscopies is addressed. Laboratory work includes molecular modeling, NMR, UV/Visible, and IR Spectroscopy. Three lectures and one laboratory period per week.

CHE 450: INSTRUMENTAL CHEMISTRY

Credits 4
The study of the theory of instrumental methods of analysis and their application in the laboratory. Topics include computers in data collection and management, UV-vis, IR, AA, fluorimetry, and electrochemical methods. In addition, NMR and mass spectrometry are covered in the lecture. Two lectures and one laboratory period per week.

CHE 460: MEDICINAL CHEMISTRY

Credits 3
Natural and synthetic medicines are investigated with attention to their fate in a living organism: absorption, distribution, and elimination; dose-response and time-response relationships of drugs; and the relationship between chemical structure and biological activity. The biochemistry of several diseases (probably including AIDS) will be examined to learn different ways that chemicals can be used to interfere with the course of a disease.

CHE 470: ADVANCED ORGANIC CHEMISTRY

Credits 3
An advanced course surveying modern organic chemistry. Topics include synthetic methods, mechanistic analysis, isotope effects, pericyclic and photochemical reactions, and electron transfer. Several case studies will be used to illustrate these topics. Three lectures per week.

CHE 480: SEMINAR IN CHEMISTRY

Credits 3
The student researches specified areas of Chemistry under the guidance of faculty members for oral presentation and defense before the class. Written papers are submitted for final review. Offered upon sufficient demand.

CHE 491–492: INDEPENDENT STUDY

Credits 3
Directed study and research in some aspect of chemistry. Open to students who have a minimum GPA of 3.0 and at least six courses in chemistry or other science. Offered by arrangement with a faculty member.

ENV 150: INTRODUCTION TO ENVIRONMENTAL SCIENCE

Credits 3
The interdisciplinary nature of environmental science will be stressed by covering the chemical, biological, and social aspects of environmental issues and problems in a case study approach. Exercises integrated into the course will expose the students to data analysis and field work associated with applied environmental work. Two or three integrated lecture-laboratory sessions per week. Required for all Environmental Science majors.

ENV 160: DYNAMIC EARTH SYSTEMS

Credits 3
Our planet is active; from the smallest drop of water to the largest continental plate the Earth is in a state of constant change. This course will explore the dynamic physical processes that shape the Earth we know today and use our knowledge of the planet’s past to predict what it will look like in the future. Topics will range from the earthquakes and volcanoes that create towering landforms to the powerfully destructive forces of rivers, tides, and winds that wear mountains into valleys. No science background is necessary.

ENV 260: WATER RESOURCES PLANNING AND MANAGEMENT

Credits 3
This is an interdisciplinary introduction to our most precious resources. Water has shaped our bodies, our planet, our history, our culture. How we manage it will shape our future. Because of increasing demand, waste, and pollution, we are depleting—and risk destroying—the limited supply of usable fresh water. This course will look at water through scientific, historical, and cultural viewpoints and survey contemporary water problems in all their dimensions—political, economic, and technological.

ENV 275: SPECIAL TOPICS IN ENVIRONMENTAL SCIENCE

Credits 3
This special topics course will explore an area of environmental science using the literature, and if appropriate, a cross-disciplinary approach. The course will allow the students and faculty an opportunity to investigate areas of environmental science that are not part of the regular curriculum.

ENV 280: COASTAL ZONE MANAGEMENT

Credits 3
This course will introduce students to the coastal environment and its resources and uses; coastal zone issues resulting primarily from human activities; the framework established by the Federal Coastal Zone Management Act for collaborative planning and regulation of the U.S. coastal zone; the roles played by the federal, state, and local governments, advocacy groups, and private property owners; the design and achievements of these programs; and international applications of coastal management. Guest speakers and case studies (e.g., Boston Harbor project, nonpoint source plans, Cape Cod Commission) will be used to illustrate themes and the intricacies of public policy development.

ENV 291: INTERNSHIP IN ENVIRONMENTAL SCIENCE

Directed study within an internship program. The student will be expected to keep a journal detailing the internship. The student will also be expected to write a paper (usually approximately 10 pages in length) summarizing an area related to the internship experience. An evaluation by the on-site supervisor will be considered when determining the grade. The student is required to have a cumulative G.P.A. of 3.0 to enroll.

ENV 350: WETLANDS

Credits 3
Wetlands play a vital role in the hydrology and ecology of global landscapes. This course will consider several topics: the function of inland and coastal marshes, swamps, and bogs in water and nutrient cycles; the influence of wetlands on biodiversity, from microbes to vertebrates; the biological links between wetlands and human activities, such as agriculture, coastal development, and fisheries; and the legal framework for the protection and restoration of endangered wetlands.

ENV 480: ENVIRONMENTAL SCIENCE SEMINAR

Credits 3
An in-depth study of a current topic in environmental science. This course will emphasize review and analysis of primary literature. Students will be expected to give oral presentations as part of the course requirements. Some example topics are global availability of drinking water in the 21st century, eutrophication, and environmental pollution control. Classes will meet for three hours weekly.

PHY 112: ASTRONOMY

Credits 3
Discover the many methods we have to observe our universe, virtually visit new planets, chat about the lives and times of the stars, and unravel the truths we can verify about the structure of our universe. This course will mix observational activities, discussion and debate, lecture, and mini experiments covering topics in astronomy.

PHY 202: GENERAL PHYSICS II

Credits 4
This course explores sound, electricity, magnetism, and light. Three lectures and one laboratory period.

PHY 213: INTRODUCTION TO ENGINEERING PROBLEM SOLVING

Credits 3
This introductory course is designed to acquaint students with the variety of engineering disciplines, as well as provide students with the basics of the engineering mindset. The ability to develop and resolve solutions to applied problems is a necessary skill for a multitude of disciplines. The structure of the course emphasizes group projects and the use of computers to create models to solve problems.

PHY 301: MECHANICS I: STATICS

Credits 3
The goal will be to endow students with a fundamental understanding of the engineering mechanics of static objects and fluids. Students will emerge proficient in problem solving, application of physical mechanical principles and critical thinking skills. This will be the first course in a year-long sequence on engineering mechanics. Topics to be covered include: Vector Algebra/Calculus, Vector forces and moments in 2-D and 3-D systems, Equivalent systems of forces, Equilibrium of rigid bodies, Centroids, centers of gravity, and distributed forces, Trusses, frames, machines: two-force and multi-force members, Beams: internal forces, shear and bending moment diagrams, Dry friction, Wedges and screws, Moments of inertia, Fluid Statics, Virtual work mechanics essentials.

PHY 302: MECHANICS II: DYNAMICS

Credits 3
This course is a 3 credits course, the second in a year-long sequence on engineering mechanics, the first being statics, a required sequence for most engineering tracks. Students will explore the fundamentals of physical-mechanical principles and apply them to the dynamics of objects and fluids. Topics to be covered include: friction forces and spring forces, power, work, and energy, momenta, impulses, and collisions, dynamics of systems of particles, kinetics of a rigid body, fluids. This course is only offered in the spring, every other year. There is no lab requirement for this course.

PHY 480: SEMINAR IN PHYSICS

Credits 3
The student researches specified areas of physics under the guidance of faculty members for oral presentation and defense before the class. Written papers are submitted for final review. Offered upon sufficient demand.

PHY 491–492: INDEPENDENT STUDY

Credits 3
Directed study in an area of Physics. The course is open to students who have completed a minimum of six science courses and have a cumulative GPA of 3.0 or higher. Offered by arrangement.